Living with a cat means love, snuggles… and the occasional accident. Whether it’s a kitten still learning or an older cat with territory issues, cat urine smells are something most pet parents deal with at some point. And let’s be real — it’s one of the most stubborn, nose-wrinkling odors to get rid of.
That’s why choosing the right cat urine remover is key. The good news? We’ve tested and reviewed some of the top-rated products on Amazon, so you don’t have to scroll endlessly or waste money on stuff that doesn’t work. From enzyme-based cleaners to natural citrus solutions, this guide helps you find the product that fits your home, your cat, and your cleaning style.
List of the Best Cat Urine Removers
THORNELL Cat Odor-Off Concentrate
Say goodbye to stubborn cat odors with THORNELL Cat Odor-Off Concentrate, a professional-grade solution trusted by veterinarians across North America. Designed to target the toughest smells — from cat urine to feces — this concentrated odor eliminator goes beyond surface-level masking. It penetrates deep into carpets, furniture, litter boxes, and even walls to neutralize odors at the source. Whether your cat had an accident or is marking their territory, this easy-to-use liquid formula restores freshness to your home in no time.
Key Features
- Veterinarian-Approved Formula: Used by professionals, safe for use in homes with pets and kids.
- Powerful Odor Neutralizer: Permanently removes cat urine and feces odors on first application.
- Non-Enzymatic Solution: Works where enzyme-based products may fail; doesn’t just cover up the smell.
- Fresh Scent: Leaves behind a pleasant, clean aroma without being overwhelming.
- Safe on All Surfaces: Apply it on carpets, floors, litter boxes, furniture, and more.
- Concentrated Power: A little goes a long way — just saturate the area, let it air dry, and you’re done.
- Stops Repeat Marking: Helps discourage your cat from returning to the same spot.
What We Like
- Super simple to use — just squeeze and soak the area.
- Actually eliminates the odor instead of just covering it up.
- Works great on multiple surfaces, from carpet to hard floors.
- Loved by pet owners and pros alike for how quickly it works.
- Safe for use around children and pets right after application.
What We Don’t Like
- Bottle cap design could be improved for easier pouring.
- The scent may be a bit strong for sensitive noses at first.
Overall
If you’re tired of trying product after product with no results, THORNELL Cat Odor-Off Concentrate is a game changer. It’s trusted by vets, easy to apply, and most importantly — it works. Whether you’re dealing with one-time messes or ongoing territorial issues, this cleaner leaves your home fresh and cat-friendly again. If you want real results, this is the cat urine remover to have in your cabinet.
Eco Strong Pet Stain and Odor Remover
Looking for a powerful way to eliminate tough cat urine smells? Eco Strong Pet Stain and Odor Remover is a pro-strength enzyme cleaner that goes straight to the source of pet messes. Whether your cat had an accident on the carpet, couch, or even your clothes, this multi-surface cleaner breaks down and digests odor-causing proteins to leave your space fresh and clean. It’s safe, non-toxic, and works on everything from litter boxes to laundry — making it a reliable go-to for any pet parent.
Key Features
- Bio-Enzymatic Power: Actively breaks down pet urine, feces, and vomit at the source — no masking.
- Large 1-Gallon Jug: Ideal for homes with multiple pets or ongoing training needs.
- Multi-Surface Use: Safe to use on carpets, hardwood, tile, furniture, clothing, and more.
- Laundry Friendly: Add to your wash cycle to remove odors from pet bedding or clothes.
- Litter Box Freshener: Spray over litter between scoops to knock out unpleasant smells.
- Made in the USA: Crafted with safety and quality in mind — non-toxic and non-corrosive.
- Pleasant Citrus Scent: Leaves behind a fresh smell without harsh chemical overtones.
What We Like
- Works impressively well on both fresh and old pet stains.
- Can be used in multiple ways — spray, soak, or add to laundry.
- Safe for homes with kids and pets, no harsh chemicals involved.
- Big bottle offers long-lasting use for serious odor control.
- Leaves no sticky residue and doesn’t stain most fabrics.
What We Don’t Like
- Requires warm water activation for best results, which takes a bit more effort.
- Scent may be a little strong right after use, especially in enclosed spaces.
Overall
If you’re dealing with cat urine, especially in tricky spots like bedding or carpet, Eco Strong Pet Stain and Odor Remover is a dependable, deep-cleaning solution. Its enzyme formula actually eliminates odors — not just covers them up — and it’s designed to be safe, effective, and flexible for all kinds of surfaces. Pet parents love it, and it’s a smart addition to your cleaning toolkit if you want lasting freshness and peace of mind.
Nature’s Miracle Cat Stain and Odor Remover
If you’ve got a cat and carpets, Nature’s Miracle Cat Stain and Odor Remover might just become your best friend. Trusted by pet parents for decades, this enzymatic cleaner is specially made to tackle the toughest feline messes — from cat pee to vomit to the dreaded hairball aftermath. It doesn’t just mask the smell; it works deep to break down odors at the source, and the light citrus scent leaves your space feeling truly clean. Whether you’re treating litter boxes, floors, or furniture, this product brings freshness back fast — and it’s safe to use around pets when used as directed.
Key Features
- Enzyme-Based Action: Breaks down and eliminates odor-causing organic stains like cat urine, feces, drool, and vomit.
- Multi-Surface Cleaner: Safe for carpets, hard floors, upholstery, and even fabrics.
- Fresh Citrus Scent: Leaves behind a light, clean scent without overwhelming your space.
- Trusted Brand: Over 35 years of helping pet owners clean up life’s messy moments.
- Pet-Safe Formula: When used as directed, it’s safe to use around your furry companions.
- Large Size for Refill Use: Comes in a 1-gallon pour bottle, perfect for homes with multiple pets.
What We Like
- Very effective on tough cat urine smells and stains.
- Enzymatic formula keeps working until the source is gone.
- Can be used in laundry for bedding and washable fabrics.
- Works great on both new and old messes with little effort.
- Generous size means fewer trips to restock.
What We Don’t Like
- The odor might intensify temporarily as it starts working.
- May require a few applications for deep or set-in stains.
Overall
Nature’s Miracle lives up to its name — especially for cat owners battling stubborn stains and smells. Its powerful enzymatic action goes deeper than surface cleaners, making it a reliable choice whether you’re cleaning litter boxes, floors, or fabric furniture. With consistent use, this cleaner becomes an essential part of maintaining a fresh, cat-friendly home.
Urine B-Gone by KINZUA ENVIRONMENTAL
If you’re struggling with lingering pet odors in your home, Urine B-Gone by KINZUA ENVIRONMENTAL brings professional-grade cleaning power in a simple spray bottle. This enzyme-based formula tackles stains and odors at the microbial level — breaking down the source of the mess instead of just covering it up. Whether you’re dealing with cat urine on carpet, dog messes on furniture, or laundry issues, this cleaner is made to restore freshness fast. It’s safe for use around the house and comes in a variety of scents to suit your space.
Key Features
- Loaded with Enzymes: Contains over 200 billion microbial colonies per bottle for deep stain and odor elimination.
- Multi-Surface Compatible: Effective on carpets, laundry, upholstery, hardwood, tile, and even drains.
- Safe for Home Use: Non-toxic and designed to be pet- and child-friendly when used as directed.
- Works on All Types of Urine: Made to tackle messes from cats, dogs, and even human accidents.
- Multiple Scents Available: Choose from Original, Citrus, or Lavender for a fresh, clean-smelling home.
- Dual-Pack Convenience: Comes in a pack of two 32 oz bottles — ideal for frequent use or multiple problem areas.
What We Like
- Super effective for removing deep-set stains and odors — even from hardwood floors.
- Great for use in laundry to rescue pet bedding and pee pads.
- Pleasant scent that freshens the space without overwhelming.
- Doesn’t leave residue or damage most surfaces.
- A go-to for households with multiple pets or long-term odor problems.
What We Don’t Like
- May take a few applications for heavy or old stains.
- The bottle cap can be tricky to open at first.
Overall
Urine B-Gone lives up to its name, offering reliable, professional-strength cleaning with the simplicity of a home spray. Whether you’ve got a new kitten, an aging dog, or a house full of pets, this formula gets the job done — leaving your home fresh and your surfaces clean. It’s one of those products that once you try it, you’ll want to keep stocked on your shelf.
Nature’s Miracle Urine Destroyer Plus Foam for Cats
Nature’s Miracle Urine Destroyer Plus Foam is a powerful solution for cat owners dealing with tough urine accidents. This foaming aerosol isn’t just surface-level — it penetrates deep into carpet fibers and padding to break down sticky, smelly urine messes. Backed by an enzymatic formula that keeps working as long as any bio-based mess remains, this cleaner helps eliminate odors at the source. With its simple spray-and-walk-away design, it’s a favorite among pet parents who want effective cleanup without the hassle of scrubbing.
Key Features
- Enzymatic Cleaning Power: Breaks down cat urine stains and odors using a bacteria-based formula.
- Deep Penetrating Foam: Expands into carpets and soft surfaces to reach hidden messes.
- Foam-to-Liquid Action: Sprays on as foam, then dissolves to get into fibers and below.
- Safe for Use at Home: Pet- and family-friendly when used as directed.
- Odor Neutralizing: Tackles strong ammonia odors and the yellow, sticky residue.
- Essential Oil Scent: Light fragrance made with essential oils — no overpowering chemical smell.
What We Like
- Super easy to apply — just spray and let it do the work.
- Works even on old or set-in urine marks with visible results.
- Safe for use on carpets, furniture, and most soft surfaces.
- Cats are less likely to return to the same spot after cleaning.
- Doesn’t have a heavy chemical smell, great for sensitive noses.
What We Don’t Like
- Foam spray is powerful and can shoot a bit farther than expected.
- May leave a temporary oily feel if overapplied in one area.
Overall
Nature’s Miracle Urine Destroyer Plus Foam is an impressive option for cat parents dealing with persistent urine messes. Its foam action makes it perfect for quick, deep cleaning — especially in high-traffic areas and on absorbent surfaces like carpet. If you’re tired of urine smells lingering in your home, this product offers a fast, effective way to get things clean and fresh again.
Nature’s Miracle Advanced Cat Stain and Odor Eliminator
When it comes to the messiest pet situations, Nature’s Miracle Advanced Cat Stain and Odor Eliminator doesn’t play around. Formulated to target even the most stubborn cat urine, vomit, and diarrhea stains, this enzymatic spray goes deep to eliminate odors at the source. Whether your cat had an accident on carpet, fabric, or furniture, this cleaner works to break down bio-based messes and discourage your kitty from going back to the same spot. It’s a favorite among cat parents who’ve tried everything — and finally found something that works.
Key Features
- Tough on Severe Messes: Formulated to handle the toughest cat messes, including old stains.
- Enzymatic Cleaning Power: Keeps working as long as any organic matter is present.
- Odor Neutralizer: Targets and eliminates strong ammonia-based smells from urine and more.
- Discourages Re-marking: Removes the odors that attract repeat accidents.
- Multi-Surface Safe: Works on carpets, hard floors, furniture, and fabrics (except untreated wood or silk).
- Trusted Brand: Backed by years of experience in pet care solutions.
What We Like
- Works great for removing both visible stains and hidden smells.
- Scent is light and fresh once dried.
- Helps stop cats from returning to the same spot.
- Comes in a spray bottle that’s easy to apply.
- Versatile enough for use all around the home.
What We Don’t Like
- May be a little strong-smelling right after use.
- Some users with sensitivities report needing to ventilate the area after spraying.
Overall
If you’re tired of cleaning the same spots over and over, Nature’s Miracle Advanced Cat Stain and Odor Eliminator offers a reliable, enzyme-powered solution that truly delivers. From new kittens to older cats with occasional accidents, it handles it all — leaving your home cleaner, fresher, and more peaceful for everyone. A solid go-to cleaner for every cat household.
Resolve Urine Destroyer Spray
Resolve Urine Destroyer Spray is a trusted go-to for pet parents who need a fast, powerful solution for pet stains and odors — especially when it comes to cat and dog urine. Using urine-elimination technology, this spray neutralizes odors on contact and removes stains in just one step. It works on both soft and hard surfaces, making it perfect for everything from carpets and rugs to furniture and car interiors. Plus, it helps prevent your pets from going back to the same spot, keeping your home fresher, longer.
Key Features
- Odor-Neutralizing Formula: Kicks in instantly to remove urine odors from cats, dogs, and more.
- Stain Removal Power: Lifts urine, food, and other tough stains from carpets and upholstery.
- Helps Prevent Repeat Accidents: Deters pets from marking the same area again.
- Versatile Cleaning: Works on most carpets, fabrics, hard surfaces, and car interiors.
- Pet-Friendly Formula: Safe for use around pets when used as directed.
- Trusted Brand: From a brand known for powerful household stain removal.
What We Like
- Starts working immediately — great for both fresh and set-in accidents.
- Easy spray bottle is mess-free and convenient to use.
- Doesn’t leave behind sticky residue.
- Can be used for both pet and human messes.
- Leaves your home smelling clean without being overpowering.
What We Don’t Like
- Some users find the scent a bit strong during application.
- Might need more than one application for deep or older stains.
Overall
For a pet stain remover that’s fast, effective, and user-friendly, Resolve Urine Destroyer Spray delivers. Whether it’s a one-time accident or an ongoing issue with a senior pet, this spray makes cleanup simple and reliable. With strong odor-fighting ingredients and proven stain-lifting power, it’s a must-have for any home with pets.
Nature’s Miracle Urine Destroyer Plus for Cats
When your cat leaves behind one of those dreaded “oops” moments, Nature’s Miracle Urine Destroyer Plus for Cats is ready to tackle it head-on. Formulated specifically to fight the powerful odors and yellow stains caused by cat urine, this enzymatic spray starts breaking down messes on contact and keeps working until the job’s done. Whether the accident happened on carpets, hard floors, or upholstery, this cleaner helps eliminate the source and freshen your space — all while being safe to use around your pets and family.
Key Features
- Targeted for Cat Urine: Designed to handle the strong scent and sticky residue of cat pee.
- Fast-Acting Enzymatic Formula: Begins breaking down stains and odors instantly and continues until the mess is gone.
- Easy to Use: Soak, wait 15 minutes, blot — that’s it.
- Eco-Minded Packaging: Made with 25% post-consumer recycled materials.
- Versatile Surface Use: Great for carpets, hard floors, furniture, and fabrics (except specialty materials like suede or silk).
- Safe for Homes: Pet- and family-friendly when used as directed.
What We Like
- Gets to work right away on even deeply set stains.
- Helps stop re-marking behavior by removing all scent traces.
- No added perfumes — great if you prefer a more neutral finish.
- Trusted brand with years of experience in pet mess cleanup.
- Spray bottle is convenient and efficient for quick application.
What We Don’t Like
- Might need more than one treatment for very old or large stains.
- Bottle design could be more durable.
Overall
Nature’s Miracle Urine Destroyer Plus for Cats delivers the kind of results cat owners need when accidents strike. From handling a surprise spray on the couch to lifting tough carpet stains, this enzymatic cleaner gets it done. It’s one of the most reliable solutions for neutralizing odors and discouraging future mishaps — a solid pick for every cat parent’s cleaning kit.
ANGRY ORANGE Pet Odor Eliminator
When cat odors take over your home, ANGRY ORANGE Pet Odor Eliminator is here to bring back the freshness. This citrus-powered spray is formulated with natural orange oil and is designed to tackle strong smells like cat urine, vomit, feces, and more. Ideal for hard surfaces and fabrics alike, it doesn’t just mask odors — it breaks them down at the source. With its bold scent and quick action, it’s a favorite among pet owners who want a cleaner home and a more pleasant environment for everyone.
Key Features
- Targets Strong Odors: Destroys tough smells from cat urine, feces, vomit, and other pet accidents.
- Powered by Natural Orange Oil: Leaves behind a fresh, clean citrus scent instead of a chemical odor.
- Multi-Surface Friendly: Works on hard floors, tile, carpet, rugs, and upholstery.
- Safe for Homes with Pets: No parabens, sulfates, or harsh chemicals when used as directed.
- Made in the USA: Proudly manufactured with attention to safety and quality.
- Highly Concentrated: A little goes a long way for long-lasting freshness.
What We Like
- Seriously effective on stubborn smells, including long-dried cat pee.
- Refreshing scent that’s strong at first but fades to neutral over time.
- Easy spray-and-go application — no complicated steps needed.
- Loved by pet rescue homes and families with multiple pets.
- Can be used in laundry rooms, near litter boxes, and even in cars.
What We Don’t Like
- Spray nozzle is known to break or leak, so transferring to another bottle may be needed.
- Can be sticky if over-applied on certain surfaces.
Overall
ANGRY ORANGE Pet Odor Eliminator packs a punch when it comes to removing pet smells from your space. It’s not just about covering up the odor — it actually clears it out, leaving behind a light citrus scent that many people love. Whether you’re cleaning up after cats, dogs, or both, this cleaner delivers fast and lasting results that help make your home feel like yours again.
Rocco & Roxie Stain & Odor Eliminator
When pet accidents happen, Rocco & Roxie Stain & Odor Eliminator steps in with a proven formula that breaks down the source of the mess — not just the smell. This enzyme-powered spray works deep into carpets, fabrics, and floors to lift stains and completely erase lingering odors. Whether you’re dealing with cat urine, vomit, feces, or other organic spills, it delivers professional-grade results without the harsh chemicals. It’s safe to use around pets and kids, and it’s even earned the Seal of Approval from the Carpet and Rug Institute.
Key Features
- Certified Safe: Chlorine-free, color-safe, and safe around children and pets.
- Enzyme Activated: Natural enzymes break down odors and stains right at the source.
- Versatile Use: Works on carpets, floors, clothing, litter boxes, kennels, and furniture.
- Eliminates Odors and Stains: Removes both the visible stain and the scent pets might revisit.
- No Harsh Residue: Leaves behind no sticky film or chemical traces.
- Trusted Performance: Over 100,000 positive reviews from pet households.
What We Like
- Excellent at preventing cats from returning to the same spot.
- Safe and gentle enough to use around the whole family.
- Has a subtle, clean scent — not overpowering or artificial.
- Cleans a wide range of materials without damage.
- Backed by a well-known, pet-friendly brand.
What We Don’t Like
- Slightly more effort needed for very old or deep stains.
- Spray bottle could be sturdier for frequent use.
Overall
Rocco & Roxie Stain & Odor Eliminator is a favorite among cat owners who need a reliable, all-purpose cleaner that actually works. Whether you’re cleaning up a fresh accident or tackling a long-term odor issue, it gives you peace of mind knowing the mess — and the smell — is gone for good. It’s a solid, go-to product to keep on hand for any pet household.
Buying Guides: What to Look for When Buying a Cat Urine Remover
Enzyme-Based Formulas
These are your best bet for deep-cleaning. Enzymes break down the proteins in cat urine, neutralizing the odor at its source rather than covering it up. Great for carpets, furniture, and older stains.
Surface Compatibility
Make sure the product is safe for the surfaces you’re cleaning — whether it’s hardwood, tile, fabric, or carpet. Many removers now work on multi-surfaces, including litter boxes and laundry.
Odor Control
Look for a product that neutralizes the smell, not one that just masks it. Some removers use essential oils (like citrus), while others have a clean or unscented finish.
Safety
Always choose a product that’s pet- and family-safe. Avoid harsh chemicals like chlorine or ammonia, especially since cats are more sensitive to scent and residue.
Bottle Size & Convenience
If you have multiple pets or frequent issues, consider a large bottle or a concentrate. For spot-cleaning, a spray bottle might be easier to manage.
Bonus Features
Some products discourage re-marking by removing scent traces that attract cats back to the same spot. Others double as laundry boosters or are certified by trusted carpet organizations.
FAQs
Enzyme cleaners break down the organic matter in urine (like proteins and ammonia crystals), which helps fully eliminate the smell. Non-enzyme cleaners may still clean the surface but might not get rid of the deeper odor.
Yes, many products are safe for sealed hardwood floors — just make sure the label mentions it. Always test in a small area first.
Use a remover that completely eliminates the scent — even one your cat can smell. Cats often return to mark spots where they smell their own or another animal’s urine.
Most high-quality enzyme cleaners like Rocco & Roxie or Nature’s Miracle are designed to work on old stains, though it might take more than one application.
They can be if used as directed, but avoid spraying directly around your cat or their belongings until the area is dry. Some cats are sensitive to strong scents like orange oil.
Yes, some options like Eco Strong and Urine B-Gone can be added to laundry to help with soiled pet bedding, clothes, or pee pads.
Conclusion
Dealing with cat urine can be frustrating, but with the right cleaner, it doesn’t have to take over your home. Whether you’re looking for a fresh citrus burst like Angry Orange or a gentle, enzyme-packed powerhouse like Rocco & Roxie, there’s a solution for every household. The key is to act fast, use a product that truly neutralizes odors, and always follow up with care that keeps your home fresh — and your cat happy.